A consolidated ever evolving technology

Best results, ergonomics, safety and flexibility for any product batch. These are the qualities that have always characterised Multispray® vacuum tray dryers, result of Italvacuum's consolidated experience in the cosmetic, pharmaceutical and chemical industry process applications.

But that’s not all, because the important added value that differentiates Multispray® innovative dryers from conventional systems is that it guarantees total cleanliness of the inner chamber and all heating plates, in compliance with the increasingly restrictive FDA standards and the cGMP standards of good manufacturing. In fact, thanks to the C.I.P. Multispray® patented fast washing system, the equipment can be completely cleaned in just a few minutes, in a repeatable and certifiable way, minimizing washing liquid consumption.

The Multispray® vacuum tray dryers can be used in any type of application as there are two versions available, fixed plate and removable plate, the latter particularly indicated for multiproduct usage.

Also, for the production of highly active pharmaceutical ingredients (high potency API) and for R&D activity, Italvacuum has developed the laboratory version LaboDry.

Multispray certifications
Applications

Pharmaceuticals

Fine Chemicals

Chemistry

Cosmetics

Food Ingredients & Additives

R&D

Total cleanliness with flexible service

The Multispray® static vacuum dryers consist of a cabinet type chamber and a series of heating plates. Both the chamber and plate surfaces are heated by the circulation of fluid.

Static dryer

Technical features:

  • Drying surface areas from 0.15 to 32 m2
  • C.I.P. MULTISPRAY® patented fast washing system
  • Optimized fluid distribution for a perfect temperature uniformity
  • Absolute precision in mechanical machining for high operating vacuums
  • Completely smooth geometry and construction and perfect polishing of the heating plates for a total and easy cleaning, in accordance with the extremely demanding cGMP standards
  • Minimum surface roughness, rounded edges and maximum internal accessibility
  • "Particle-free" trays for complete product recovery
  • Nitrogen diffuser for a uniform gas flow on every single plate
  • Heated door as an additional process guarantee
  • Ready for installation in clean room
  • Airtight door cladding
  • Automatic door opening system.
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Laboratory version

The LaboDry laboratory version was developed for the treatment of highly active pharmaceutical ingredients (high potency API) and to meet the production requirements of small batches. The laboratory version features separate cell construction and skid-mounted auxiliary accessories, ready for installation in a glove box

Fixed shelves version

Total cleanliness and absence of any contaminating agents is essential for highly valued and delicate pharmaceutical products. The fixed shelves version satisfies such requirements thanks to the smooth geometry of the heating plates, minimum surface roughness, rounded edges and easy inner accessibility. Also, to make cleaning operations easier, the base of the cabinet is tilted towards the door in order to facilitate the removal and discharge of the washing water. With a wide front flange and the set-back supporting systems, through the wall installation is possible, further isolating the clean room from the technical area.

Extractable shelves version

The Multispray® dryer with extractable shelves ensures all the advantages of the fixed plate version, but offers an important added value: it is equipped with shelves mounted on a completely removable single structure, guaranteeing total accessibility to all the internal surfaces exposed to the process. An innovation that makes total cleaning even easier and minimizes the risk of cross contamination in case of frequent changeover operations.

The connection to the heating circuit by means of two fast couplings outside the chamber, allows the plate pack removal without a previous discharge of the heating fluid from within.

The plate pack is removed with the aid of an external hydraulic trolley, completely made of stainless steel and equipped with antistatic polymer wheels. With this trolley the operator can quickly handle the plate pack in extreme safety and without any difficulty. In addition, by using an external hydraulic trolley, no rails or wheels are needed inside the cabinet, that would make cleaning and swab testing really difficult.

The Italvacuum systems comply with ATEX directives and cGMP standards.

From laboratory to installation: the best way to choose the right industrial equipment

Italvacuum has a complete range of pilot systems, allowing to carry out laboratory and semi-industrial drying tests on customer’s products.
During the test it is possible to take product samples for analysis and change the process parameters at any moment, to define the ideal drying cycle procedure. In this way clients have the possibility to make the most suitable technological decisions for their own requirements.
The execution of the tests is completed and documented with a detailed report on the evolution of the main parameters and conclusions on the tests results.

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Drying tests

Guarantee of total cleanliness

The Multispray® vacuum tray dryers were conceived to make the cleaning operations extremely fast, efficient, repeatable and certifiable. With the C.I.P. Multispray® patented fast washing system – consisting of C.I.P. diffuser and mobile washing unit - the chamber and inner shelves can be cleaned in just a few minutes, minimizing liquid consumption. This is the great added value that distinguishes Multispray® dryers from the conventional static dryers. In addition to total cleanliness of inner parts, this unique washing system protects the operator’s safety, by avoiding prolonged contact with possible product residues and solvents present inside the dryer. Also, the perfect airtight closure and the Multispray® special design eliminate any risk of washing liquid contamination in the surrounding environment.

C.I.P. Multispray® Diffuser

The C.I.P. Multispray® diffuser, equipped with washing nozzles capable of efficiently cleaning the walls and inner shelves, is quickly installed onto the dryer door. The nozzles have been specially designed and developed by Italvacuum in materials compatible with the process to guarantee maximum cleaning efficiency with minimum consumption of washing liquid.

Mobile washing unit

The mobile washing unit consists of a stainless steel tank complete with a PTFE membrane and pneumatic pump, which feeds the C.I.P. diffuser perfectly, guaranteeing maximum cleaning efficiency.
The washing cycle is operated and managed by a pneumatic control board situated on the mobile unit. Only a connection to compressed air is sufficient to make the system work. A valve allows the external collection of contaminated liquid after washing has been carried out, or alternatively its recirculation. A further guarantee against liquid contamination of the surrounding environment.
The mobile washing unit is equipped with antistatic polymer wheels, in compliance with ATEX directives and cGMP standards, and also enabling easy and safe handling.

Certified efficiency

The C.I.P. Multispray® patented fast washing system ensures an efficiency of more than 98% for plates inside the cabinet and of 100% with the plate pack extracted from the drying chamber. This result is certified by a washing test carried out by specialised personnel and proved with the use of riboflavin as a tracer substance.
Washing operations carried out with the Multispray® system guarantee perfect and repeatable results.

External cleaning

The Multispray® vacuum tray dryers are easy to clean also externally, thanks to the airtight door cladding. In addition the wide front flange and the set-back supporting system allows through the wall installation, further separating the clean room from the technical area.

Strengths

  • Maximum production flexibility
  • Best results and efficiency even for small batches
  • Ideal for multiproduct applications and fast changeover operations
  • With the C.I.P. MULTISPRAY® patented fast washing system the chamber and inner shelves can be completely cleaned in just a few minutes, in a repeatable and certifiable way and with minimum liquid consumption
  • Perfect temperature uniformity
  • High operating vacuum
  • Completely smooth geometry and construction, perfect polishing of heating plates
  • Absolute care in manufacturing details
  • "Particle-free" trays for complete product recovery
  • Ideal ergonomics, maximum ease of use and total safety
  • Ready for installation in clean room.

All the quality of an integrated system

In addition to the Multispray® vacuum tray dryer, Italvacuum can also supply components to complete the system, appropriately dimensioned to meet every process requirement:

  • Saurus939 high vacuum pump
  • Vacuum condensation group for reduction of drying times and recovery of extracted solvents
  • Heating and cooling group for system thermal regulation
  • PLC control board for total system management, equipped with software in compliance with the CFR 21 Part 11 standard, that guarantees the reproducibility of dried batches and can interface with centralized control systems.
Vacuum dryer - Multispray

The ideal solution for any processing

The Italvacuum static vacuum dryers are available in a vast range of dimensions.


Fixed shelves version
 
Modello EO,2 S EO,5 S E1 S E1,5 S E1,75 S E2,5 S E3,5 S
Inner volume lt 250 600 1150 1530 1960 2730 4000
Inner dimensions
(W x D x H)
mm 570x560x790 670x1060x840 1040x1060x1045 1040x1060x1385 1270x1060x1455 1550x1060x1660 1550x1560x1660
Number of heating shelves -- 6 7 9 11 13 15 15
Heating shelves dimension
(W x D)
mm 500x500 600x1000 970x1000 970x1000 1200x1000 1480x1000 1480x1480
Number of trays -- 6 14 36 44 52 90 60
Trays dimensions
(W x D x H)
mm 480x480x40 600x480x40 480x480x40 480x480x40 600x480x40 480x480x40 710x710x40
Useful surface area m2 1,4 4 8,3 10 15 20,7 30,2

W = width D = depth H = height

Extractable shelves version

Modello EO,33 P.E E0,9 P.E E1,6 P.E E2,7 P.E E3.9 P.E E5.5 P.E
Inner volume lt 340 900 1660 2600 3400 5200
Inner dimensions
(W x D x H)
mm 600x650x870 760x1185x1000 1140x1185x1230 1380x1185x1590 1660x1185x1720 1820x1685x1690
Number of heating shelves -- 6 7 9 13 15 28
Heating shelves dimension
(W x D)
mm 500x500 600x1000 970x1000 1200x1000 1480x1000 750x1500
Number of trays -- 6 14 36 52 90 56
Trays dimensions
(W x D x H)
mm 480x480x40 600x480x40 480x480x40 600x480x40 480x480x40 750x750x40
Useful surface area m2 1,4 4 8,3 15 20,7 31,5

W = width D = depth H = height

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